Δ8-THC
Chemistry
- Formula
- C21H30O2
- Molar mass
- 314.5 g/mol
- IUPAC name
- (6aR,10aR)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
- InChIKey
- HCAWPGARWVBULJ-IAGOWNOFSA-N
Chemistry from PubChem CID 638026.
Also known as
- 5957-75-5
- delta-8-tetrahydrocannabinol
- DELTA8-Tetrahydrocannabinol
- delta8-THC
- DELTA-8-THC
- delta-6-THC
- trans-DELTA8-Tetrahydrocannabinol
- DTXSID20878586
Stereoisomers
4 distinct stereoisomers are registered for this structure.
- Delta-8-Tetrahydrocannabinol this area CID 638026
- (6aS,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol CID 9883343
- delta8-Tetrahydrocannabinol, (6as-cis)- CID 23815440
- (6aR,10aS)-6,6,9-trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol CID 86308458
- 6,6,9-Trimethyl-3-pentyl-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol mixture CID 2977
Attribution
Raphael Mechoulam — discovered its activity, 1995
Clinical antiemetic use. With A. Abrahamov and A. Abrahamov, gave Δ8-THC to eight children on chemotherapy across 480 treatments and reported vomiting completely prevented with negligible side effects; the trial began in 1987 and was published in Life Sciences in 1995. He did NOT first make Δ8-THC — Roger Adams's group prepared it in the early 1940s.
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