Opioids
Anything acting at the μ/κ/δ opioid receptors — natural, semi-synthetic and fully synthetic.
General Morphinans The opium skeleton and its derivatives. Legal Mitragynines Kratom indole alkaloids and their semi-synthetic derivatives. Fentanyls 4-anilidopiperidines. The dominant adulterant risk in the opioid supply. Receptors Nature Nitazenes 2-benzylbenzimidazoles. Potent non-fentanyl synthetics. Chemistry Oripavines Thebaine-derived, including the partial agonists used in maintenance. Addiction Help Open-chain Opioids Diphenylpropylamines — no rigid ring system. Phenylpiperidines Pethidine and relatives. Benzamide Opioids The U-series and AH-7921. Other Synthetic Opioids Atypical scaffolds and dual-mechanism agents. Antagonists & Reversal Overdose reversal and blockade. Harm-reduction critical.
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