Gordon Alles
A pharmacologist rather than a synthetic chemist, and his contribution is discovery rather than invention. Amphetamine already existed when in 1929 he established what it does — self-experimenting while looking for an ephedrine substitute for asthma — and he prepared and patented the sulfate salt that Smith, Kline & French sold as Benzedrine. He did the same for MDA in 1930, taking 126 mg and describing the effects, though he did not publish that account until 1959.
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- Entactogens
- MDA C10H13NO2 discovered its activity, 1930
First recorded human psychoactive dose. MDA itself was made by Carl Mannich and Willy Jacobsohn in 1910.
- Stimulants
- Amphetamine C9H13N discovered its activity, 1929
Established the stimulant effect by self-experiment, and patented the sulfate salt sold as Benzedrine.