Tramadol
Chemistry
- Formula
- C16H25NO2
- Molar mass
- 263.37 g/mol
- IUPAC name
- cis-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol
- InChIKey
- TVYLLZQTGLZFBW-ZBFHGGJFSA-N
Chemistry from PubChem CID 33741.
Also known as
- 27203-92-5
- Ralivia flashtab
- Ralivia ER
- Tramadon
- cis-Tramadol
- Biomadol
- Contramid
- Labesfal
Stereoisomers
4 distinct stereoisomers are registered for this structure.
- Tramadol this area CID 33741
- trans-Tramadol CID 63015
- (-)-(S,S)-trans-Tramadol CID 667511
- Tramadol, trans-(-)- CID 9813907
- 2-((Dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol mixture CID 5523
Sold as the racemate, and unusually both enantiomers earn their place: (+)-tramadol and its M1 metabolite carry the opioid action and serotonin reuptake inhibition, while (−)-tramadol inhibits noradrenaline reuptake. Separating them would not give you a better tramadol, it would give you two different and weaker drugs.
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