CH₃CH₃

Buprenorphine

Chemistry

75 atoms · Conformer computed and published by PubChem.
Formula
C29H41NO4
Molar mass
467.6 g/mol
IUPAC name
(1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol
InChIKey
RMRJXGBAOAMLHD-IHFGGWKQSA-N

Chemistry from PubChem CID 644073.

Also known as

  • Temgesic
  • 52485-79-7
  • Buprenophine
  • Buprenorfina
  • Buprenorphinum
  • Butrans
  • (-)-buprenorphine
  • buprenorphin

Stereoisomers

13 distinct stereoisomers are registered for this structure.

  • Buprenorphine this area CID 644073
  • (1R,2S,6R,14R,15S,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 5311033
  • Npc32169 CID 9811785
  • Buprenorphine component OF alks-5461 CID 9848990
  • (1S,2S,6R,14R,15R,16S)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 21680235
  • (1S,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2R)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 40473187
  • (1R,2R,6S,14S,15S,16S)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 51005861
  • (1S,2S,6S,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 73265270
  • (1S,2S,6R,14S,15S,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 98104370
  • (1R,2R,6R,14S,15R,16S)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 129157178
  • (1R,2S,6R,14S,15S,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 131632123
  • (1R,2S,6R,14R,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 135390184
  • (1S,2S,6R,14S,15R,16R)-5-(cyclopropylmethyl)-16-[(2S)-2-hydroxy-3,3-dimethylbutan-2-yl]-15-methoxy-13-oxa-5-azahexacyclo[13.2.2.12,8.01,6.02,14.012,20]icosa-8(20),9,11-trien-11-ol CID 162529591
  • 17-(Cyclopropylmethyl)-18-(2-hydroxy-3,3-dimethylbutan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol mixture CID 2476

Photographs

packaging Fan of sealed Suboxone 8 mg/2 mg sachets, each holding one buprenorphine/naloxone sublingual film; the blue-and-white foil pouches are the form most people recognize.
Fan of sealed Suboxone 8 mg/2 mg sachets, each holding one buprenorphine/naloxone sublingual film; the blue-and-white foil pouches are the form most people recognize.
Jr de Barbosa ·CC BY-SA
packaging Pharmacy stock bottle of generic buprenorphine and naloxone 8 mg/2 mg sublingual tablets (Roxane Laboratories), marked CIII; the tablet form that preceded the film.
Pharmacy stock bottle of generic buprenorphine and naloxone 8 mg/2 mg sublingual tablets (Roxane Laboratories), marked CIII; the tablet form that preceded the film.
Tmeers91 ·CC BY-SA
packaging Generic buprenorphine/naloxone 8 mg/2 mg sublingual film pouch (Dr. Reddy's): plain white foil with lot and expiry stamp, the low-cost counterpart to branded Suboxone sachets.
Generic buprenorphine/naloxone 8 mg/2 mg sublingual film pouch (Dr. Reddy's): plain white foil with lot and expiry stamp, the low-cost counterpart to branded Suboxone sachets.
Sintegral ·CC BY-SA
General Open discussion — anything that fits nowhere narrower. no posts yet Legal Scheduling status, pending actions, and where the law actually stands. no posts yet Dosage Dose ranges by route, and the margins between them. no posts yet Experiences First-hand reports — set, setting, and what actually happened. no posts yet Chemistry Structure, synthesis, and analytical chemistry. no posts yet Interactions Combination risks — what must not be mixed, and why. no posts yet Addiction Help Dependence, withdrawal, and where to find real help. no posts yet
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