CH₃CH₃

JWH-200

Chemistry

53 atoms · Conformer computed and published by PubChem.
Formula
C25H24N2O2
Molar mass
384.5 g/mol
IUPAC name
[1-(2-morpholin-4-ylethyl)indol-3-yl]-naphthalen-1-ylmethanone
InChIKey
SZWYXJHTNGJPKU-UHFFFAOYSA-N

Chemistry from PubChem CID 10045570.

Also known as

  • 1-(2-(4-Morpholinyl)ethyl)-3-(1-naphthoyl) indole
  • JWH 200
  • UNII-9HN5J913P3
  • DEA No. 7200
  • HSDB 8000
  • 1-(2-(4-Morpholinyl)ethyl)-3-(1-naphthoyl)indole
  • J378.966G
  • DTXSID60145946

Attribution

  • John W. Huffman — popularised it, 1991

    CORRECTION TO THE USUAL STORY: despite the JWH code, this is not Huffman's compound. 1-(2-Morpholin-4-ylethyl)-3-(1-naphthoyl)indole was made at Sterling Drug (Sterling Winthrop) in 1991 as WIN 55,225, in the aminoalkylindole programme that also produced pravadoline and WIN 55,212-2. Huffman's group re-synthesised and re-tested it as a reference compound and gave it a notebook number; because the JWH label is the one that reached the drug market, it is now almost always filed under his name. Ki ~42 nM at CB1, about the same as THC. Role recorded as 'popularised' rather than 'first-synthesis' for that reason.

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