CH₃CH₃

JWH-175

Chemistry

50 atoms · Conformer computed and published by PubChem.
Formula
C24H25N
Molar mass
327.5 g/mol
IUPAC name
3-(naphthalen-1-ylmethyl)-1-pentylindole
InChIKey
TYBRSILIYTUTSQ-UHFFFAOYSA-N

Chemistry from PubChem CID 56603534.

Also known as

  • 619294-35-8
  • 1H-Indole, 3-(1-naphthalenylmethyl)-1-pentyl-
  • 3S82KAS832
  • 3-(1-Naphthalenylmethyl)-1-pentyl-1H-indole
  • 3-(naphthalen-1-ylmethyl)-1-pentyl-1H-indole,
  • RefChem:150682
  • TYBRSILIYTUTSQ-UHFFFAOYSA-N
  • JWH 175

Attribution

  • John W. Huffman — first synthesis, 2003

    (1-Pentylindol-3-yl)naphthalen-1-ylmethane — JWH-018 with the ketone replaced by a plain methylene bridge, Ki 22 nM at CB1, several times weaker than JWH-018. From Huffman, Mabon, Wu et al., '3-Indolyl-1-naphthylmethanes' (Bioorg. Med. Chem. 11:539–549, 2003), which argued for aromatic stacking rather than hydrogen bonding at CB1. The abstract uses numbered compounds rather than JWH codes, so the code-to-paper mapping comes from the Huffman-series list.

    source

No posts here yet.

harm reduction · community · honest information