CH₃CH₃

JWH-122

Chemistry

52 atoms · Conformer computed and published by PubChem.
Formula
C25H25NO
Molar mass
355.5 g/mol
IUPAC name
(4-methylnaphthalen-1-yl)-(1-pentylindol-3-yl)methanone
InChIKey
HUKJQMKQFWYIHS-UHFFFAOYSA-N

Chemistry from PubChem CID 44466638.

Also known as

  • 619294-47-2
  • DEA No. 7122
  • JWH 122
  • 44147RI31X
  • J2.929.917J
  • DTXSID00210965
  • RefChem:792606
  • DTXCID30133456

Attribution

  • John W. Huffman — first synthesis, 2005

    1-Pentyl-3-(4-methyl-1-naphthoyl)indole, the 4-methyl analogue of JWH-018 and one of the most potent compounds in the series (Ki 0.69 nM CB1, 1.2 nM CB2). Attributed to the 2005 Huffman naphthoylindole SAR paper on steric and electronic effects of naphthoyl substituents; the Wikipedia Ki table instead cites the 2003 naphthylmethanes paper, so the exact first report is not settled. Banned in Sweden on 1 October 2010 after appearing in herbal blends.

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