JWH-030

Chemistry

Also known as

• 162934-73-8
• Naphthalen-1-yl(1-pentyl-1H-pyrrol-3-yl)methanone
• Methanone, 1-naphthalenyl(1-pentyl-1H-pyrrol-3-yl)-
• D3WWBII0GZ
• 1-naphthalenyl(1-pentyl-1h-pyrrol-3-yl)methanone
• RefChem:1055999
• Naphthalen-1-yl-(1-pentylpyrrol-3-yl)methanone
• JWH 030

Attribution

• JW

  John W. Huffman — first synthesis, 1995

  1-Pentyl-3-(1-naphthoyl)pyrrole, the archetype of the naphthoylpyrroles, introduced in Lainton, Huffman, Martin and Compton, '1-Alkyl-3-(1-naphthoyl)pyrroles: a new class of cannabinoid' (Tetrahedron Lett. 36:1401–1404, 1995). A CB1 partial agonist, Ki 87 nM — roughly half THC's potency — and the demonstration that the indole ring could be cut down to a pyrrole.

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