HU-210
Chemistry
- Formula
- C25H38O3
- Molar mass
- 386.6 g/mol
- IUPAC name
- (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
- InChIKey
- SSQJFGMEZBFMNV-WOJBJXKFSA-N
Chemistry from PubChem CID 9821569.
Also known as
- 112830-95-2
- HU 210
- HU210
- (-)-HU-210
- (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol
- 191042422P
- DTXSID30150188
- (6aR,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo(c)chromen-1-ol
Stereoisomers
4 distinct stereoisomers are registered for this structure.
- HU 210 this area CID 9821569
- Dexanabinol CID 107778
- (6aR,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol CID 23872172
- (6aS,10aR)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol CID 23955915
- 9-(Hydroxymethyl)-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromen-1-ol mixture CID 4193475
Attribution
Raphael Mechoulam — first synthesis, 1988
The (-)-enantiomer of the 1,1-dimethylheptyl analogue of 11-hydroxy-Δ8-THC, made from (1R,5S)-myrtenol in his group at the Hebrew University — 'HU' stands for Hebrew University. Reported with Feigenbaum, Lander, Segal, Järbe, Hiltunen and Consroe; 100-800x the potency of THC. The paper's point was that cannabinoid activity is stereospecific.
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