Noladin ether
Chemistry
- Formula
- C23H40O3
- Molar mass
- 364.6 g/mol
- IUPAC name
- 2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoxy]propane-1,3-diol
- InChIKey
- CUJUUWXZAQHCNC-DOFZRALJSA-N
Chemistry from PubChem CID 6483057.
Also known as
- 222723-55-9
- 2-AG ether
- 2-arachidonyl glyceryl ether
- 2-Arachidonyl Glycerol ether
- 2-[(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoxy]propane-1,3-diol
- 5Z,8Z,11Z,14Z-eicosatetraen-2-glyceryl ether
- 2-(5Z,8Z,11Z,14Z-eicosatetraenyl)-sn-glycerol
- CHEBI:75913
Attribution
Lumír Ondřej Hanuš — isolated it, 2001
First author on Hanus L, Abu-Lafi S, Fride E, et al., PNAS 98:3662 (2001), isolating the compound from porcine brain and showing CB1 agonism.
Raphael Mechoulam — isolated it, 2001
An ether-type endocannabinoid isolated from porcine brain, binding CB1 with Ki 21.2 nM. Hanuš, Abu-Lafi, Fride, Breuer, Vogel, Shalev, Kustanovich, Mechoulam, PNAS 98:3662-3665. Mechoulam is senior author.
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