Psilocybin: legal

Psilocybin is Schedule I under US federal law [1], and psilocin is separately Schedule I under the same regulation [1]. Both are also Schedule I under the 1971 UN Convention on Psychotropic Substances [2]. Nothing here is legal advice, and nothing on this page substitutes for checking the current law and its analogue or "controlled substance analogue" provisions where you are.

Psilocybin was placed on Schedule I in 1970, during a period when it had risen sharply in recreational popularity [3]. It has since received breakthrough therapy designation from the FDA for treatment-resistant depression [4] and for major depressive disorder [4].

References

1. 21 CFR § 1308.11 Schedule I — Electronic Code of Federal Regulations (eCFR)
2. Convention on Psychotropic Substances, 1971 — United Nations (UNODC)
3. DARK Classics in Chemical Neuroscience: Psilocybin — ACS Chemical Neuroscience
4. Psilocybin for Mental Health and Addiction: What You Need To Know | NCCIH — National Center for Complementary and Integrative Health (NIH)