Albert Hofmann

1906–2008 · Swiss · Sandoz Laboratories, Basel

Working on ergot alkaloids at Sandoz, Hofmann first synthesized LSD-25 in 1938 and set it aside; he discovered its effects only in 1943, after accidental exposure. He went on to isolate and synthesize psilocybin and psilocin from Psilocybe mexicana, giving both compounds their first defined chemistry. The same programme produced methylergometrine, still used to control post-partum haemorrhage.

Compounds credited overall: numerous ergot derivatives; the LSD, psilocybin and psilocin work is the lasting part

On this site

• Psychedelics
• LSD C20H25N3O first synthesis, 1938
• LSD C20H25N3O discovered its activity, 1943

  Discovered by accidental absorption, then confirmed deliberately on 19 April 1943.

• Psilocybin C12H17N2O4P isolated it, 1958

  Isolated from Psilocybe mexicana, then synthesized.

• LSA (Ergine) C7H5NO3S isolated it, 1960

  Identified as the active principle of ololiuqui morning glory seeds.

Sources

• https://en.wikipedia.org/wiki/Albert_Hofmann