Etomidate

Chemistry

34 atoms · Conformer computed and published by PubChem.

Formula: C14H16N2O2
Molar mass: 244.29 g/mol
IUPAC name: ethyl 3-[(1R)-1-phenylethyl]imidazole-4-carboxylate
InChIKey: NPUKDXXFDDZOKR-LLVKDONJSA-N

Chemistry from PubChem CID 667484.

Also known as

33125-97-2
Hypnomidate
Amidate
(+)-Etomidate
D-Etomidate
Etomidato
Etomidatum
ethyl 1-[(1R)-1-phenylethyl]-1H-imidazole-5-carboxylate

Stereoisomers

2 distinct stereoisomers are registered for this structure.

Etomidate this area CID 667484
1H-Imidazole-5-carboxylic acid, 1-((1S)-1-phenylethyl)-, ethyl ester CID 6338045
Ethnor mixture CID 36339

Attribution

Paul Janssen — first synthesis, 1964
Janssen Pharmaceutica under his direction (code R 16659); Janssen is first author on the 1971 paper introducing it. Still a standard induction agent for haemodynamically unstable patients. Family name is invented — the site's vocabulary has no general-anaesthetic bucket.

source

Photographs

Amidate (Hospira, US): etomidate injection USP, 20 mg/10 mL (2 mg/mL) single-dose fliptop vial with blue cap, labeled for intravenous use only.

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