Astemizole
Chemistry
- Formula
- C28H31FN4O
- Molar mass
- 458.6 g/mol
- IUPAC name
- 1-[(4-fluorophenyl)methyl]-N-[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]benzimidazol-2-amine
- InChIKey
- GXDALQBWZGODGZ-UHFFFAOYSA-N
Chemistry from PubChem CID 2247.
Also known as
- 68844-77-9
- Hismanal
- Paralergin
- Histamen
- Retolen
- Astemison
- Astemizol
- Astemizolum
Attribution
Janssen Pharmaceutica under his direction; bench chemistry by F. Janssens and colleagues with Paul Janssen as senior author (J Med Chem 1985), first pharmacology 1981, marketed 1983 as Hismanal. Withdrawn 1999 for cardiac arrhythmia. Year given is first publication, not necessarily synthesis.
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