Miconazole
Chemistry
- Formula
- C18H14Cl4N2O
- Molar mass
- 416.1 g/mol
- IUPAC name
- 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
- InChIKey
- BYBLEWFAAKGYCD-UHFFFAOYSA-N
Chemistry from PubChem CID 4189.
Also known as
- 22916-47-8
- Daktarin IV
- Miconazol
- Miconazolo
- Miconazolum
- 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
- Daktarin
- Oravig
Stereoisomers
2 distinct stereoisomers are registered for this structure. This area's record is the racemate — the mixture, which is normally the form encountered.
- Miconazole this area mixture CID 4189
- (S)-miconazole CID 969503
- (R)-Miconazole CID 1150344
Attribution
Paul Janssen — first synthesis, 1969Janssen Pharmaceutica under his direction: the bench chemistry was by E.F. Godefroi and Jan Heeres, with Janssen as senior author on the 1969 J Med Chem paper (patented 1968). This paper is the start of the whole Janssen azole antifungal line. Family name is invented — the site has no antifungal family.
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