Domperidone

Chemistry

54 atoms · Conformer computed and published by PubChem.

Formula: C22H24ClN5O2
Molar mass: 425.9 g/mol
IUPAC name: 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
InChIKey: FGXWKSZFVQUSTL-UHFFFAOYSA-N

Chemistry from PubChem CID 3151.

Also known as

57808-66-9
Motilium
Domperidona
Domperidonum
R 33,812
R-33812
NSC299589
NSC-299589

Attribution

Paul Janssen — first synthesis, 1974
Janssen Pharmaceutica under his direction (code R 33 812), designed out of the antipsychotic work as a dopamine antagonist that does not cross the blood-brain barrier. Janssen is senior author on the 1978 papers introducing it.

source

Photographs

Nauzelin (domperidone) 10 mg blister sheets from Japan, front and back: small round white tablets marked KH306 in foil printed '10mg', sold by Kyowa Kirin as a gastrointestinal motility agent.

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