Diphenoxylate
Chemistry
- Formula
- C30H32N2O2
- Molar mass
- 452.6 g/mol
- IUPAC name
- ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
- InChIKey
- HYPPXZBJBPSRLK-UHFFFAOYSA-N
Chemistry from PubChem CID 13505.
Also known as
- Difenoxilato
- 915-30-0
- Diphenoxylatum
- Difenossilato
- ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate
- R-1132
- 1-(3-Cyano-3,3-diphenylpropyl)-4-phenyl-isonipecotic acid ethyl ester
- Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylisonipecotate
Attribution
Paul Janssen — first synthesis, 1956Janssen personally, as part of his pethidine-variation programme; the peripherally-acting antidiarrhoeal use came out of screening opioids for gut effects. Later sold as Lomotil.
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