Lofentanil
Chemistry
- Formula
- C25H32N2O3
- Molar mass
- 408.5 g/mol
- IUPAC name
- methyl (3S,4R)-3-methyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
- InChIKey
- IMYHGORQCPYVBZ-NBGIEHNGSA-N
Chemistry from PubChem CID 65499.
Also known as
- Lofentanilum
- Lofentanila
- 61380-40-3
- 7H7YQ564XV
- DTXSID201016402
- R-32792
- Lofentanilo
- (-)-METHYL CIS-3-METHYL-1-PHENETHYL-4-(N-PHENYLPROPIONAMIDO)ISONIPECOTATE
Stereoisomers
4 distinct stereoisomers are registered for this structure.
- Lofentanil this area CID 65499
- methyl (3R,4R)-3-methyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate CID 6328619
- 3-Methyl-1-phenethyl-4-(phenyl-propionyl-amino)-piperidine-4-carboxylic acid methyl ester CID 10070040
- methyl (3S,4S)-3-methyl-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidine-4-carboxylate CID 22795178
- Methyl 3-methyl-4-[(1-oxopropyl)phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate mixture CID 123642
Attribution
Janssen Pharmaceutica under his direction, from the same 1976 Van Bever/Janssen 4-anilinopiperidine series as carfentanil and sufentanil. Never marketed; year is the publication of the series, not necessarily the synthesis.
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