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Dosage

Amounts, by route, and the distance between them: where an effect begins, what a common range looks like, where that range ends, and how much of a gap sits between a wanted dose and one that hurts. Route belongs to every figure on this page — the same amount swallowed, insufflated, vaporised or injected is not the same exposure, and onset and duration change with it. So does the material: a salt and a freebase weigh differently, plant and extract vary batch to batch, and a blotter or a pressed pill is a claim about content, not a measurement of it.

Numbers here describe populations, not the reader. Tolerance, body, other drugs, prescribed medicines and a liver enzyme somebody inherited all move them. Where no reliable data exists this page says so rather than estimating, and an absence of published figures is not evidence that a margin is wide.

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