Depressants
Sedative-hypnotics. Mostly GABAergic, and the class where cross-tolerance and additive respiratory depression kill.
Benzodiazepines The 1,4- and triazolo- benzodiazepines, prescribed and designer. General Legal Thienodiazepines Thiophene-for-benzene benzodiazepine analogues. Receptors Z-Drugs Non-benzodiazepine GABA-A positive modulators. Barbiturates Barbituric acid derivatives. Nature Chemistry Gabapentinoids α2δ calcium-channel ligands. Addiction Help GHB & Analogues GHB and its prodrugs. Alcohols Ethanol and other drinkable alcohols. Quinazolinones Methaqualone and relatives. Carbamates Meprobamate and carisoprodol. Kavalactones Kava and its lactones.
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