CH₃CH₃

Sertraline

Chemistry

37 atoms · Conformer computed and published by PubChem.
Formula
C17H17Cl2N
Molar mass
306.2 g/mol
IUPAC name
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
InChIKey
VGKDLMBJGBXTGI-SJCJKPOMSA-N

Chemistry from PubChem CID 68617.

Also known as

  • 79617-96-2
  • (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
  • (+)-Sertraline
  • Sertralina
  • Sertralinum
  • cis-(+)-sertraline
  • Cp 51974
  • (1S,4S)-sertraline

Stereoisomers

4 distinct stereoisomers are registered for this structure.

  • Sertraline this area CID 68617
  • Sertraline, cis-(-)- CID 54375
  • (1S,4R)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine CID 6093397
  • Sertraline, trans-(A+-)- CID 9882979
  • 4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine mixture CID 5203

Unusually for an SSRI, sertraline was developed and is sold as one specific stereoisomer, the (1S,4S) form. The other three exist only in the laboratory.

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