Duloxetine
Chemistry
- Formula
- C18H19NOS
- Molar mass
- 297.4 g/mol
- IUPAC name
- (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
- InChIKey
- ZEUITGRIYCTCEM-KRWDZBQOSA-N
Chemistry from PubChem CID 60835.
Also known as
- 116539-59-4
- (S)-Duloxetine
- Yentreve
- (3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
- 2-Thiophenepropanamine, N-methyl-gamma-(1-naphthalenyloxy)-, (gammaS)-
- Duloxetina
- LY248686
- O5TNM5N07U
Stereoisomers
2 distinct stereoisomers are registered for this structure.
- Duloxetine this area CID 60835
- (R)-Duloxetine CID 10334821
- (+-)-Duloxetine mixture CID 122252
Attribution
Named inventor with David Robertson and Joseph Krushinski on US 4,956,388 (filed 1986, granted 1990), and first author on the 1988 Life Sciences paper describing the racemate LY227942 as a dual serotonin/norepinephrine uptake inhibitor. The (+)-enantiomer, LY248686, became duloxetine.
General Open discussion — anything that fits nowhere narrower. no posts yet Legal Scheduling status, pending actions, and where the law actually stands. no posts yet Dosage Dose ranges by route, and the margins between them. no posts yet Experiences First-hand reports — set, setting, and what actually happened. no posts yet Chemistry Structure, synthesis, and analytical chemistry. no posts yet Interactions Combination risks — what must not be mixed, and why. no posts yet
No posts here yet.