Anton Köllisch
Synthesized MDMA at Merck in 1912 as an intermediate in a route to a haemostatic drug. Nobody tested it for psychoactivity and Köllisch died in the First World War without learning what he had made.
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- Entactogens
- MDMA C11H15NO2 first synthesis, 1912
Made at Merck as a synthetic intermediate; never tested for psychoactivity.