Louisiana adds MGM-15, MGM-16 and mitragynine pseudoindoxyl to Schedule I by emergency rule

Louisiana's Department of Health has added mitragynine pseudoindoxyl, MGM-15 (dihydro-7-hydroxymitragynine) and MGM-16 (9-fluoro-dihydro-7-hydroxymitragynine) to Schedule I of the state's Uniform Controlled Dangerous Substances Law, by emergency rule.

The rule adds all three substances to Schedule I [1], naming mitragynine pseudoindoxyl [1], MGM-15 [1] and MGM-16 [1] specifically. Control extends to any isomer, ester, ether or salt of the three, including salts of isomers, esters and ethers [1]. The one carve-out: none of this applies to these substances when they are part of a pharmaceutical product approved by the FDA [1].

For anyone in Louisiana, that means mitragynine pseudoindoxyl, MGM-15 and MGM-16 are controlled as Schedule I substances under state law, except when they are part of an FDA-approved pharmaceutical product [1].

Procedurally, the Department of Health adopted this as an emergency rule rather than a final, permanently-adopted one [1]. The Secretary's stated basis was a finding that Schedule I control is necessary to prevent an imminent peril to public health [1]. It stays in effect only for the maximum period Louisiana's Administrative Procedure Act allows for emergency rules, or until a final rule is adopted to take its place, whichever happens first [1]. That means the permanent version of this scheduling has not been finished — the emergency rule is what is currently operative, and a separate rulemaking process is what would make the listing permanent.

Also reported: WDSU 6 New Orleans, LDH adds three substances to Schedule I.

References

1. Declaration of Emergency: Added Controlled Dangerous Substances (LAC 46:LIII.2704), Louisiana Register LR 52, October 2026, 2610#001 — Louisiana Department of Health, Office of Public Health, in the Louisiana Register (Office of the State Register)