| Substance | Tennessee | Federal |
|---|---|---|
| 7-OH (7-hydroxymitragynine) | not checked yet | pending: Temporary Placement of 7-Hydroxymitragynine Above a Specified Threshold in Schedule I |
| MGM-15 | not checked yet | Controlled substance (in effect since 2026-08-26) |
| Mitragynine pseudoindoxyl | not checked yet | Controlled substance (in effect since 2026-08-26) |
| Kratom (leaf and extracts) | Banned (in effect since 2026-07-01) | Restricted |
| Nitrous oxide (whippets, tanks) | Banned (in effect since 2026-07-01) | Regulated; pending: H.R. 7945, Nitrous Oxide Safety Act of 2026 |
| Hemp THC and THCA | not checked yet | Regulated; pending: Public Law 119-103, division B, § 2019; restricted from 2026-12-11 |
| Tianeptine | not checked yet | pending: Schedules of Controlled Substances: Placement of Tianeptine in Schedule I |
| Phenibut | not checked yet | not checked yet |
| Poppers (alkyl nitrites) | not checked yet | Banned (in effect since 1991-02-27) |
| SR-17018 (5,6-dichloro desmethylchlorphine) | not checked yet | Controlled substance (in effect since 2026-08-27) |
it is an offense to knowingly manufacture deliver or sell kratom
this act takes effect july 1 2026
House Bill 1649 / Senate Bill 1656, "Matthew Davenport's Law" (bill text; enacted without amendment as Public Chapter 950) Tennessee General Assembly
Our note: Read from the bill text on the legislature's site; the public chapter PDF itself was not read for this line.
It is unlawful for a retail seller to sell or offer for sale nitrous oxide.
This act takes effect July 1, 2026, the public welfare requiring it.
SB 1843 / HB 1644, Senate Amendment No. 1 (the adopted text, enacted as Public Chapter 702) Tennessee General Assembly
Our note: A retail-sale ban; manufacturers, distributors and wholesalers may still sell for medical, dental and food uses. Read from the adopted amendment; the public chapter PDF itself was not read for this line.