Bryan Molloy
With Klaus Schmiegel, synthesized the compound series that produced fluoxetine, working from a project Molloy and Ray Fuller began in 1970. David Wong then retested the series for serotonin-selective reuptake inhibition and identified fluoxetine as the most selective of them. It was not the first SSRI to reach a market — zimelidine was, in 1982, and was withdrawn within about eighteen months — but it was the first to succeed commercially, and it changed how depression is treated.
On this site
Sort
- Antidepressants
- Fluoxetine C17H18F3NO first synthesis, 1972
With Klaus Schmiegel, from a project begun with Ray Fuller in 1970.